CA125 غير مفيد في التنبؤ بسرطان غدي بطانة الرحم بين نزيف ما بعد انقطاع الطمث

Abstract

Postmenopausal bleeding (PMB) is vaginal bleeding that happens at least 12 months after your periods have stopped. This study was conducted in Ibb governorate during 2 years to determine the value of serum CA 125 in predicting endometrial adenocarcinoma among postmenopausal bleeding women. The study included 40 PMB women with age range (45-80 years) and mean of 59.9±8.9 years. Diagnosis of the endometrial curettage revealed 8(20.0%) endometrial adenocarcinoma and 19(80.0%) benign endometrial lesions. The mean CA125 was 26.8±19.7 U/mL, it did not show significant difference between PMB due to endometrial adenocarcinoma or other benign endometrial lesions. This study concluded that measuring serum CA125 is not useful in predicting endometrial adenocarcinoma among post menopausal bleeding women and recommended gynecologist to rely only on histopathological diagnosis among PMB women.