The relation between age, gender and the percentage of abnormalities in the RBC Morphology

Abstract

 Age and gender represents biologic variables that can modulate the pathophysiology and severity of human diseases, including RBC disorders. Recent reports have indicated that stored RBCs from male donors hemolyze more than those from female donors at the end of storage or in response to applied mechanical stress. The main purpose of this study was to determine the relation between age, gender and percentage of abnormalities in the RBC, to known variation RBC abnormality in women and men. Ninety eight blood slides of 49 individuals comprised of 21 male and 28 female of different age classes were collection and subjected to full history taking and Laboratory examination. In general, the Chi square (χ²) test exhibited statistical significant effects of age on RBC morphology (χ² = 166.89, P=0.000). During the current study, 10 different types of abnormality in shapes of the red blood cells were identified in male samples and 11 types in female samples. In conclusion, The age and gender effects on the human blood cells were evaluated. There was a significant albeit very small difference in RBC abnormality between women and men in the entire cohort.